The Evidence Hub
A Central Home for African-Led Evidence. Ensuring transparency, accessibility, and global visibility of health research.
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11 Records Found
Global prevalence and correlates of mpox vaccine acceptance and uptake: a systematic review and meta-analysis
Sahabi Kabir Sulaiman, Fatimah Isma’il Tsiga-Ahmed, Muhammad Sale Musa, Bello Tijjani Makama, Abdulwahab Kabir Sulaiman & Tijjani Bako Abdulaziz
Reference DOI: doi.org/10.1038/s43856-024-00564-1Global prevalence and correlates of mpox vaccine acceptance and uptake: a systematic review and meta-analysis
Mpox is an infection caused by the monkeypox virus and is transmitted through direct contact with infected animals or people, or indirectly through contact with contaminated materials. An unprecedented mpox outbreak spanning all continents occurred in 2022. Vaccination against the infection by high-risk groups, including the LGBTQI+ community and frontline healthcare workers has been recommended by the WHO as essential to outbreak control. To investigate the rates and factors associated with mpox vaccine acceptance and uptake across population subgroups (LGBTQI+ community, healthcare workers, people living with HIV, and the general public), we undertook this global systematic review and meta-analysis of the available evidence. Our results reveal substantial global and regional variations in the rates of mpox vaccine acceptance and uptake across population groups, with wide acceptance-uptake gaps, indicating the need for behavioral interventions to increase mpox vaccine confidence and uptake.
Incidence of postpartum depression among women with postpartum haemorrhage in Kano, northern Nigeria
Fatimah Isma’il Tsiga-Ahmed, Sahabi Kabir Sulaiman
Reference DOI: doi.org/10.1038/s44294-024-00031-1Incidence of postpartum depression among women with postpartum haemorrhage in Kano, northern Nigeria
The burden of postpartum depression (PPD), an important but largely neglected cause of maternal morbidity, is often increased by the presence of common co-morbidities, such as postpartum haemorrhage (PPH). Additionally, stress and the absence of social support can amplify PPD risk. Understanding the relationship between these conditions will help identify at-risk women and allow prompt intervention. Using a prospective cohort design, we recruited 72 women who had experienced PPH and another 72 women who had not within 24 h of delivery to assess the risk of PPD among them. The cumulative incidence of PPD among all participants was 15.3% (19/124). There was insufficient evidence to suggest that women with PPH have a higher risk of PPD than women without PPH (OR: 1.32; 95% CI: 0.55–3.13). Poor social support and high perceived stress increased the risk of PPD. We recommend screening for PPD among women with high perceived stress and low social support.
Depression mediates the relationship between exposure to stigma and medication adherence among people living with HIV in low-resource setting: a structural equation modeling approach
Sahabi Kabir Sulaiman, Muhammad Sale Musa, Fatimah Isma’il Tsiga-Ahmed, Saidu Idris Ahmad, Salisu Abubakar Haruna, Abdullahi Abdurrahman Zubair, Bello Tijjani Makama, Aminu Hussein, Abdulwahab Kabir Sulaiman, Farouq Muhammad Dayyab & Abdulaziz Tijjani Bako
Reference DOI: link.springer.com/article/10.1007/s10865-024-00488-0Depression mediates the relationship between exposure to stigma and medication adherence among people living with HIV in low-resource setting: a structural equation modeling approach
This study hypothesizes that depression mediates the association between exposure to stigma and medication non-adherence in people living with HIV (PLHIV). We recruited 372 PLHIV from the Stigma, health-related Quality of life, antiretroviral Adherence, and Depression among people living with HIV (SQuAD-HIV) project, a multicenter cross-sectional study conducted between October 2021 and February 2022 among PLHIV attending six ART clinics in two geopolitical regions of northern Nigeria. A structural equation modeling (SEM) framework, utilizing the full information maximum likelihood estimator, was used to elucidate the pathways linking stigma, depression, and ART medication adherence, adjusting for sociodemographic characteristics. The total number of eligible participants analyzed (353) included 32.7% male PLHIV with a mean age (SD) of 39.42 (10.14). Being female was positively associated with adherence (β, 95% CI 0.335, 0.163–0.523, p-value < 0.001) but negatively associated with stigma (β, 95% CI − 0.334, − 0.561 to − 0.142, p-value = 0.001), while urban residence was negatively associated with stigma (β, 95% CI − 0.564, − 0.804 to − 0.340, p-value < 0.001). Our analysis also indicated that a higher level of experienced stigma was associated with decreased medication adherence. This association was partially mediated by depression (indirect effect = (0.256) (− 0.541) = − 0.139; p-value < 0.01). The proportion of the association between stigma and medication adherence explained through mediation by depression was 35.6%. These findings underscore the need for targeted interventions aimed at lowering exposure to stigma among PLHIV to improve medication adherence.
Changes in sleep, physical activity, and health behaviors among Nigerian fasting adults in Ramadan during the COVID-19 pandemic
Fatimah Isma’il Tsiga-Ahmed, Sahabi Kabir Sulaiman, Muhammad Saleh Musa, Aminu Hussein, Saidu Idris Ahmad, Rabiu Ibrahim Jalo, MoezAlIslam Faris, Ahmed S BaHammam, Syed Fahad Javaid, Moien AB Khan
Reference DOI: www.ovid.com/jnls/jehp/fulltext/10.4103/jehp.jehp_1579_23~changes-in-sleep-physical-activity-and-health-behaviors?context=latestarticlesChanges in sleep, physical activity, and health behaviors among Nigerian fasting adults in Ramadan during the COVID-19 pandemic
Sleep and Physical Activity During Ramadan in Nigeria Background and Objective There is a lack of comprehensive data regarding how sleep, physical activity, and health behaviors change among the public during Ramadan, particularly in the context of the coronavirus pandemic. To address this gap, researchers conducted a nationwide study assessing the factors influencing shifts in sleep and physical activity among adult Nigerian Muslims observing diurnal fasting. Study Methodology Researchers utilized an online cross sectional design employing snowball sampling to survey exactly seven hundred and seventy adults. They evaluated sleep and physical activity metrics using adapted versions of the International Physical Activity Questionnaire Short Form and the Copenhagen Psychosocial Questionnaire. The gathered data was then analyzed utilizing logistic regression models to identify significant behavioral correlates. Key Findings The statistical analysis revealed notable shifts in daily routines during the fasting period: Physical Activity: Approximately thirty nine percent of participants reported a decrease in physical activity. Factors strongly associated with physical activity changes included female sex, obesity, and experiencing good sleep. Sleep Quality: Over half of respondents reported experiencing good sleep. Improved self reported sleep quality was highly correlated with maintaining a perceived good health state and sleeping at least seven to nine hours daily. Conclusion Despite physical activity decreasing for a third of participants, the vast majority experienced good sleep. Strategies utilizing intermittent fasting can successfully promote positive healthy lifestyle changes today.
Examination of sleep in relation to dietary and lifestyle behaviors during Ramadan: A multi-national study using structural equation modeling among 24,500 adults amid COVID-19
Khan MAB, BaHammam AS, Amanatullah A, Obaideen K, Arora T, Ali H, Cheikh Ismail L, Abdelrahim DN, Al-Houqani M, Allaham K, Abdalrazeq R, Aloweiwi WS, Mim SS, Mektebi A, Amiri S, Sulaiman SK, Javaid SF, Hawlader MDH, Tsiga-Ahmed FI, Elbarazi I, Manggabarani S, Hunde GA, Chelli S, Sotoudeh M, Faris ME and Ramadan Intermittent Fasting Collaborators (2023) Examination of sleep in relation to dietary and lifestyle behaviors during Ramadan: A multi-national study using structural equation modeling among 24,500 adults amid COVID-19.
Reference DOI: www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2023.1040355/fullExamination of sleep in relation to dietary and lifestyle behaviors during Ramadan: A multi-national study using structural equation modeling among 24,500 adults amid COVID-19
Dietary and Lifestyle Impacts on Sleep During Ramadan Background and Objective Approximately 1.5 billion Muslims worldwide observe the holy month of Ramadan. Fasting significantly alters sleep patterns, which in turn profoundly impacts overall human health. Because sleep is intimately connected to daily behaviors, this comprehensive global study aimed to evaluate how specific dietary and lifestyle changes affect sleep parameters during the fasting month. Study Methodology Researchers conducted a massive cross-sectional study, disseminating a structured, electronic questionnaire across twenty-seven different global countries in thirteen languages. The survey assessed independent variables like diet and lifestyle against dependent sleep parameters, specifically quality, duration, and disturbance. The team utilized structural equation modeling to rigorously analyze the data from the 24,541 enrolled adults. Key Findings The extensive and rigorous statistical analysis uncovered several significant lifestyle correlations during Ramadan: Sleep Duration: Achieving optimal sleep (seven to nine hours) was strongly associated with engaging in sufficient physical activity and consuming plant-based proteins. Sleep Quality: Participants who frequently consumed vegetables, fruits, dates, and plant-based proteins reported significantly better sleep quality. Additionally, minimizing screen time and reducing the intake of delivered foods improved overall rest. Sleep Disturbances: Smoking was directly linked to both greater sleep disturbances and drastically diminished sleep quality. Conclusion To ensure healthy sleep while observing Ramadan fasting, individuals should prioritize consuming fruits, vegetables, and plant-based proteins, alongside maintaining regular physical activity and also strictly avoiding smoking.
A systematic review and meta-analysis of the global prevalence and determinants of COVID-19 vaccine acceptance and uptake in people living with HIV
Sahabi Kabir Sulaiman, Muhammad Sale Musa, Fatimah Isma’il Tsiga-Ahmed, Abdulwahab Kabir Sulaiman & Abdulaziz Tijjani Bako
Reference DOI: doi.org/10.1038/s41562-023-01733-3A systematic review and meta-analysis of the global prevalence and determinants of COVID-19 vaccine acceptance and uptake in people living with HIV
Summary of COVID-19 Vaccine Uptake Among PLHIV Background People living with HIV (PLHIV) face an elevated risk from severe SARS-CoV-2 infections. To better understand vaccination behaviors within this specific group, researchers conducted a systematic review and meta-analysis of 54 studies encompassing 167,485 participants, published through August 2023. Global Rates The analysis established a global COVID-19 vaccine acceptance rate of 67.0% and an overall uptake rate of 56.6%. While both metrics demonstrated modest growth between the years 2020 and 2022, severe geographical disparities emerged: The European Region led globally in acceptance and uptake, followed closely by the Americas. Conversely, the Eastern Mediterranean and African regions recorded the lowest actual vaccination rates globally, despite reporting a moderate general acceptance among their populations. Influencing Factors Demographic and psychological determinants heavily influenced whether individuals received the vaccine: Men, individuals aged 40 and older, and those with a recent influenza vaccination were significantly more likely to get vaccinated. High acceptance strongly correlated with trusting vaccine efficacy, recognizing personal susceptibility to the virus, and fearing its specific impact on HIV. Lower vaccination rates were disproportionately observed among Black, Latinx/Hispanic, and mixed-race populations, plus individuals facing unemployment or holding lower education levels. Conclusion Although global willingness to vaccinate gradually improved, significant demographic and regional inequalities still remain. Protecting this highly vulnerable population requires sustained, highly targeted public health interventions addressing the socioeconomic barriers preventing actual vaccine uptake.
COVID-19 vaccine hesitancy among people living with HIV in a low-resource setting: A multi-center study of prevalence, correlates and reasons
Sahabi Kabir Sulaiman, Muhammad Sale Musa, Fatimah Isma'il Tsiga-Ahmed, Farouq Muhammad Dayyab, Abdulwahab Kabir Sulaiman, Bashir Dabo, Saidu Idris Ahmad, Salisu Abubakar Haruna, Abdullahi Abdurrahman Zubair, Aminu Hussein, Sadiya Usman , Jummai Usman Wada, Ayoola Yekeen Ayodele, Muhammed Wulgo Ali, Bello Tijjani Makama , Abdulaziz Tijjani Bako, The SQuAD-HIV collaborators
Reference DOI: doi.org/10.1016/j.vaccine.2023.02.056COVID-19 vaccine hesitancy among people living with HIV in a low-resource setting: A multi-center study of prevalence, correlates and reasons
Highlights • Approximately 13% of the study participants have received at least one dose of the COVID-19 vaccine. • Nearly six in ten unvaccinated participants were hesitant to accept the COVID-19 vaccine. • Age ≥50 years, unemployment, and past ART adverse reaction are associated with lower odds of hesitancy. • Females and those attending ART clinics located in the states’ capitals have higher odds of hesitancy. • Major reasons for COVID-19 vaccine hesitancy included fear of adverse effects and doubts about the vaccine’s efficacy.
Perceived changes in the mental well-being among Nigerians due to Ramadan Intermittent Fasting during the COVID-19 pandemic
Sahabi Kabir Sulaiman, Fatimah Isma’il Tsiga-Ahmed, Muhammad Sale Musa
Reference DOI: doi.org/10.1002/brb3.2990Perceived changes in the mental well-being among Nigerians due to Ramadan Intermittent Fasting during the COVID-19 pandemic
Introduction: Muslims fast every year during the month of Ramadan from dawn until dusk. This study examined mental well-being and correlating factors among Nigerian adults who observed Ramadan intermittent fasting (RIF). Methods: A validated generalized anxiety disorder-2 and Patient Health Questionnaire-2, the four-item spiritual well-being index, and the Islamic intrinsic religiosity questionnaire were used to collect data about mental well-being (depression, anxiety), spirituality, and intrinsic religiosity through a web-based survey between the May 9, 2021 (27th of Ramadan, 1442) and the June 4, 2021 (29th of Shawwal, 1442). We studied the mental well-being of respondents over a period of 4 weeks before Ramadan (BR) and during the 4 weeks of Ramadan between the April 12, 2021 and the May 12, 2021(DR). Multinomial regression analysis was used to determine the factors associated with depression and anxiety. This research did not receive any grant or funding.
A systematic review and meta-analysis of the prevalence of caregiver acceptance of malaria vaccine for under-five children in low-income and middle-income countries (LMICs)
Sahabi Kabir Sulaiman, Muhammad Sale Musa, Fatimah Ismail Tsiga-Ahmed, Farouq Muhammad Dayyab, Abdulwahab Kabir Sulaiman, Abdulaziz Tijjani Bako
Reference DOI: doi.org/10.1371/journal.pone.0278224A systematic review and meta-analysis of the prevalence of caregiver acceptance of malaria vaccine for under-five children in low-income and middle-income countries (LMICs)
Background and Objective This systematic review evaluated the global acceptance rate of the approved RTS,S malaria vaccine and identified key factors influencing its uptake. Because malaria remains the second leading cause of pediatric mortality, predominantly affecting children in developing countries, widespread vaccine adoption is critical for reducing global incidence and death rates. Methodology Researchers systematically searched six major databases, including PubMed and the WHO repository, adhering to PRISMA guidelines. They analyzed eleven quantitative studies published in English that assessed the willingness of individuals to accept a free malaria vaccine. The final analysis encompassed 14,666 total participants and utilized a random effects model to determine pooled prevalence, while thoroughly checking for publication bias and study heterogeneity. Key Findings The statistical analysis revealed an overwhelmingly positive response to the vaccine: Overall Acceptance: The aggregate global acceptance rate was exceptionally high at 95.3%. Demographics: Acceptance was slightly higher among the general population (96.3%) compared to mothers (94.4%). Regional Variance: Nigeria demonstrated the highest willingness to vaccinate (97.6%), followed closely by Ghana (94.6%) and Tanzania (92.5%). Barriers and Conclusion Vaccine acceptance was significantly influenced by various sociodemographic factors, including age, sex, occupation, religion, and geographic residence. Conversely, primary barriers to acceptance centered on safety apprehensions, doubts regarding vaccine efficacy, the logistical burden of multiple required injections, and overall low public awareness. Ultimately, future public health initiatives must directly address these logistical and educational barriers to ensure theoretical willingness translates into actual vaccine uptake across the vulnerable global health landscape.
Nigerian Muslim’s Perceptions of Changes in Diet, Weight, and Health Status during Ramadan: A Nationwide Cross-Sectional Study
Sahabi Kabir Sulaiman, Fatimah Isma’il Tsiga-Ahmed, MoezAlIslam E. Faris, Muhammad Sale Musa, Udoyen Abasi-okot Akpan, Abdullahi Muhammad Umar, Salisu Maiwada Abubakar, Kholoud K. Allaham, Taif Alyammahi, Munther A. Abdbuljalil, Syed Fahad Javaid, and Moien AB Khan
Reference DOI: doi.org/10.3390/ijerph192114340Nigerian Muslim’s Perceptions of Changes in Diet, Weight, and Health Status during Ramadan: A Nationwide Cross-Sectional Study
Background and Study Objective During the Islamic month of Ramadan, Muslims fast from dawn to sunset, significantly altering daily dietary habits. This nationwide cross-sectional study aimed to assess how these modifications impact food choices, perceived body weight, and overall health status among adult Nigerian Muslims. Study Methodology Researchers conducted a web-based survey of 770 adult Nigerian Muslims (predominantly women, average age 27.7 years). The survey evaluated eating behaviors, dietary choices, and perceived changes in weight and health. Data was analyzed using a logistic regression model to identify key predictors of weight and health status shifts. Key Findings The survey results revealed a strong shift toward healthier dietary behaviors during the fasting month: Dietary Improvements: Participants reported consuming more fruits, palm dates, vegetables, milk products, and homemade meals. Conversely, the intake of energy drinks, sugary beverages, salty snacks, and pastries significantly decreased. Weight Dynamics: Over half of the respondents (54.6%) experienced weight loss during Ramadan, while 37.0% maintained their weight, and only 8.4% reported weight gain. Health Status: A vast majority (97.3%) reported experiencing good overall health during fasting, with only 2.7% noting a decline in health. Conclusion Ramadan fasting in Nigeria is associated with significant weight loss and positive dietary modifications. Public health initiatives should leverage these findings to encourage citizens to maintain these healthier eating habits year-round.
Impact of the COVID-19 Pandemic on Elderly Medical Admissions and Outcomes in a Tertiary Hospital in Northeastern Nigeria: A Comparative Retrospective Study
Sahabi Kabir Sulaiman, Fatimah Isma’il Tsiga-Ahmed, Muhammad Sale Musa
Reference DOI: www.wajmed.orgImpact of the COVID-19 Pandemic on Elderly Medical Admissions and Outcomes in a Tertiary Hospital in Northeastern Nigeria: A Comparative Retrospective Study
BACKGROUND: The coronavirus infectious disease 2019 (COVID-19) has been shown to be more lethal in the elderly (>65 years), especially those with co-morbidities. This study examined the impact of the pandemic lockdown period on trends in elderly medical admissions and deaths. METHODOLOGY: This is a retrospective study of elderly medical admissions and deaths in the medical wards of a Nigerian hospital. Data for the months of March, April, May, June, and July of 2020 was compared to the same months before (2019) and after (2021). Analysis was done using STATA version 15.0. RESULTS: During the study period, two hundred and seventysix elderly patients were admitted, with a mean age of 73.4 +- 7.4 years. The most common diagnoses at admission were chronic kidney disease (CKD) (26.85%, n=74) and hypertensive heart disease (HHD) (21.7%, n=60). The highest admission was in 2021, with a total of 99 (35.9%). Overall, 60 mortalities were recorded, with a proportional mortality rate of 21.7%, which was highest in 2020 (25.0%) and lowest in 2021 (17.1%). There was no difference between the mortality rates of 2019 versus 2020 (P=0.82) and 2020 versus 2021(P=0.18). Sepsis (35.0%) and CKD (25.0%) were the major contributors in 2019. CONCLUSION: CKD and HHD were the most common diagnoses at admission, whereas sepsis, CKD, and CVD were the commonest causes of death. The Covid-19 pandemic did not significantly alter the elderly admission pattern in our setting. WAJM 2022; 39(12): 1238–1244. Keywords: COVID-19, Elderly, Admission pattern, Mortality.
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All materials hosted in the Evidence Hub adhere to ethical research standards, transparent authorship, and reproducibility. By amplifying African-led research, we contribute to a more balanced global health evidence base.
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